Industry – Page 34 – Swanson Reed | Specialist R&D Tax Advisors

MS INBRE Imaging Facility Upgrades Equipment for Research

cryo-TEM at MSU Lets Scientists Explore Molecules

Mississippi IDeA Network of Biomedical Research Excellence (INBRE) intends to enhance the already cutting edge technology used in their Imaging Facility.

The INBRE Imaging Core has upgraded its Leica SP8 confocal microscope to the STELLARIS STED super resolution platform to achieve one of the most complete imaging systems in the region. This imaging facility offers both imaging and microscopy expertise to researchers throughout the entire state and offers both access and training to the biomedical research equipment.

Adding the STELLARIS STED super resolution microscope into the mix will enhance quality and scope of biomedical research throughout the state. These super-resolution microscopes open up the breadth of objects that can be imaged. Classic microscopes are limited by the physics of light itself. The super-resolution tech can image dynamic objects within cells, and even nanoparticles created in the lab.

The Leica STELLARIS STED is an upgrade to the previous confocal microscope, offering a 3D STimulated Emission Depletion (STED) super resolution module. The STED technology enables fluorescence microscopy approaches for visualizing objects smaller than the diffraction limit of light and can increase resolution up to 10x more than a traditional microscope.

“Microscopes are essential tools for the investigation of biological and molecular systems,” Dr. Lindner, the director of the Imaging Facility, said. “Access to cutting-edge instruments is vital for cell biology, embryology, biochemistry, and imaging advanced materials. Further, the addition of the advanced microscope will provide important training opportunities for students, also enhancing Mississippi STEM education.”

Mississippi INBRE, directed by USM Professor Dr. Mohamed Elasri, is a statewide program supported by an award from the National Institutes of General Medical Sciences. Its mission is to enhance the biomedical foundation in Mississippi and engage talented researchers and students in biomedical research projects that will increase the state’s research competitiveness, as well as positively impact the health of the state’s citizens.

Are you developing new software for an existing application? Did you know your development work could be eligible for the R&D Tax Credit and you can receive up to 14% back on your expenses? Even if your development isn’t successful your work may still qualify for R&D credits (i.e. you don’t need to have a patent to qualify). To find out more, please contact a Swanson Reed R&D Specialist today or check out our free online eligibility test.

Who We Are:

Swanson Reed is one of the U.S.’ largest Specialist R&D tax advisory firms. We manage all facets of the R&D tax credit program, from claim preparation and audit compliance to claim disputes.

Swanson Reed regularly hosts free webinars and provides free IRS CE and CPE credits for CPAs. For more information please visit us at www.swansonreed.com/webinars or contact your usual Swanson Reed representative.

Parvizi Surgical Innovations Announces Investment and Collaboration with Efferent Health

Parvizi Surgical Innovations, LLC has just announced both investment and partnership with a new startup – Efferent Health, LLC. This collaboration is aimed at improving connection and automation of healthcare.

Pennsylvania-based Parvizi is dedicated to improving patient outcomes through the development of unique and innovative technologies.

Efferent Health is also an information technology company focused on developing solutions to better join operational processes and improve efficiencies.

Together, they will work on the development of the FHIR cloud-based healthcare platform. Titled FHIR, this Fast Healthcare Interoperability Resource solution will help create a secure exchange of health information.The existing technology solutions are limited in their abilities to access digital data and crosstalk across platforms. Collaboration of resources and talent would help to improve and leverage innovative technology for patients and improve their care.

Are you developing new software for an existing application? Did you know your development work could be eligible for the R&D Tax Credit and you can receive up to 14% back on your expenses? Even if your development isn’t successful your work may still qualify for R&D credits (i.e. you don’t need to have a patent to qualify). To find out more, please contact a Swanson Reed R&D Specialist today or check out our free online eligibility test.

Who We Are:

Swanson Reed is one of the U.S.’ largest Specialist R&D tax advisory firms. We manage all facets of the R&D tax credit program, from claim preparation and audit compliance to claim disputes.

Swanson Reed regularly hosts free webinars and provides free IRS CE and CPE credits for CPAs. For more information please visit us at www.swansonreed.com/webinars or contact your usual Swanson Reed representative.

ClearFlame Engine Technologies Receives Funding to test Clean Diesel-style Fuel

ClearFlame Engine Technologies has announced they have successfully acquired $2.5 million in additional financing from multiple Corn Grower Associations, including the Iowa Corn Growers Association. This funding will help ClearFlame deploy pilot Class 8 trucks with its patented technology.

ClearFlame is a growing startup whose focus is on clean engine technologies. Their research leverages diesel-style mixing-controlled compression ignition (MCCI). Historic attempts in the industry have tested the use of clean-burning fuels and fuels that are easily made from waste CO2 have failed to ignite using MCCI.

ClearFlame’s solutions have been validated and combat the ignition limitations by elevating combustion temperatures. This elevation allows the use of non-traditional fuels without sacrificing performance. It even increases power by 25%.

Their technology can be integrated into existing diesel engine platforms and offer a more sustainable and cost-effective solution than diesel fuel while utilizing the existing liquid fuel infrastructure. They intend to use this latest funding to get a series of Class 8 trucks deployed by the end of 2021.

Are you developing new technology for an existing application? Did you know your development work could be eligible for the R&D Tax Credit and you can receive up to 14% back on your expenses? Even if your development isn’t successful your work may still qualify for R&D credits (i.e. you don’t need to have a patent to qualify). To find out more, please contact a Swanson Reed R&D Specialist today or check out our free online eligibility test.

Who We Are:

Swanson Reed is one of the U.S.’ largest Specialist R&D tax advisory firms. We manage all facets of the R&D tax credit program, from claim preparation and audit compliance to claim disputes.

Swanson Reed regularly hosts free webinars and provides free IRS CE and CPE credits for CPAs. For more information please visit us at www.swansonreed.com/webinars or contact your usual Swanson Reed representative.

IN3 Announces David Beering as VP of Hypersonics

The Indiana Innovative Institute (IN3) has named David Beering the new Vice President of Hypersonics. IN3 works with academia, industry, and government to create a hub of national security innovation to help in solving critical defense priorities.

David Beering has been invested in developing space systems to further the economy and national security interests. In addition to contributing work at IN3, he is the owner of Intelligent Designs, LLC and co-founder of Continuous Satellite Data, LLC – two companies focused on delivering innovative solutions to the satellite industry.

The Hypersonics division is set on solving the hypersonic national security threat. They are working on furthering hypersonic technology through better modeling, improved simulation capability, and increased collaboration. David Beering will bring his extensive experience to help further this division and improve the development of solutions.

Are you developing new software for an existing application? Did you know your development work could be eligible for the R&D Tax Credit and you can receive up to 14% back on your expenses? Even if your development isn’t successful your work may still qualify for R&D credits (i.e. you don’t need to have a patent to qualify). To find out more, please contact a Swanson Reed R&D Specialist today or check out our free online eligibility test.

Who We Are:

Swanson Reed is one of the U.S.’ largest Specialist R&D tax advisory firms. We manage all facets of the R&D tax credit program, from claim preparation and audit compliance to claim disputes.

Swanson Reed regularly hosts free webinars and provides free IRS CE and CPE credits for CPAs. For more information please visit us at www.swansonreed.com/webinars or contact your usual Swanson Reed representative.

Georgia Tech and NREL Will Collaborate on Energy Research

The Georgia Institute of Technology and the Department of Energy’s National Renewable Energy Laboratory (NREL) have entered into an agreement with the intention of improving scientific output of both institutions. They intend to create a collaborative environment to better support projects undertaken and improve access to technology and equipment,

This collaboration has three main goals:

1. Solve Big Problems – through leveraging the integrated full weight of intellectual capabilities and infrastructure of both parties in a multi-disciplinary and institutional manner.

Sustain and Engage Human Capital – by exposing a pipeline of talent to problems or practical importance and complex nature early in their academic programs.

Accelerate Technology Adoption – by introducing new ideas, science, and technology into the industrial and federal marketplace of jointly developed intellectual property.

“We are excited about this MOU, which will facilitate expanded collaboration between NREL and Georgia Tech’s esteemed faculty and first-rate students,” said Peter Green, deputy laboratory director and science and technology officer at NREL. “Together we will leverage the significant intellectual, research, and infrastructure capabilities of both institutions to address some of the critical large-scale, complex research challenges facing industry during the energy transition.”

The agreement will span at least five years and was introduced as a result of the increasing complexity of energy related research.

Are you developing new technology for an existing application? Did you know your development work could be eligible for the R&D Tax Credit and you can receive up to 14% back on your expenses? Even if your development isn’t successful your work may still qualify for R&D credits (i.e. you don’t need to have a patent to qualify). To find out more, please contact a Swanson Reed R&D Specialist today or check out our free online eligibility test.

Who We Are:

Swanson Reed is one of the U.S.’ largest Specialist R&D tax advisory firms. We manage all facets of the R&D tax credit program, from claim preparation and audit compliance to claim disputes.

Swanson Reed regularly hosts free webinars and provides free IRS CE and CPE credits for CPAs. For more information please visit us at www.swansonreed.com/webinars or contact your usual Swanson Reed representative.

AFRL Renovates and Reopens

The Air Force Research Laboratory (AFRL) has just opened their newly renovated R&D facility in Ohio. The new renovations will allow AFRL scientists and engineers to conduct multidisciplinary research with easy access to biotech and organic synthesis equipment and infrastructure.

“Creating collaborative spaces allows employees to increase productivity and propel the next-generation of aerospace vehicles and technologies,” said Dr. Michael Gregg, the director of AFRL’s Aerospace Systems Directorate. They believe the large-scale renovations will help in the discovery and development of affordable air and space technologies for use by the Department of Air Force.

Are you developing new software for an existing application? Did you know your development work could be eligible for the R&D Tax Credit and you can receive up to 14% back on your expenses? Even if your development isn’t successful your work may still qualify for R&D credits (i.e. you don’t need to have a patent to qualify). To find out more, please contact a Swanson Reed R&D Specialist today or check out our free online eligibility test.

Who We Are:

Swanson Reed is one of the U.S.’ largest Specialist R&D tax advisory firms. We manage all facets of the R&D tax credit program, from claim preparation and audit compliance to claim disputes.

Swanson Reed regularly hosts free webinars and provides free IRS CE and CPE credits for CPAs. For more information please visit us at www.swansonreed.com/webinars or contact your usual Swanson Reed representative.

cryo-TEM at MSU Lets Scientists Explore Molecules

Montana State University has developed a new microscope that brings research to a whole new, teeny, tiny level. They have just recently powered up their second ultra-high resolution cryogenic transmission electron microscope (cryo-TEM).

The cryo-TEM can create high-resolution and 3D images at a cellular level with greater clarity than any other tool available. In fact, it can successfully capture images down to a tenth of a nanometer with high-resolution images.

In order to achieve this high resolution they had to design the lenses to be suspended on air cushions to avoid even tiny vibrations. Even a change in temperature would lead to slight contractions or expansions and cause distortions.

Along with the microscope, the Cryo-EM lab now has an entire room dedicated to the computers that take the images captured by the TEM — as many as 100,000, up to 50 per second — and stitch them into a 3-D model of something normally invisible to the naked eye.

“It will hugely benefit this campus and I’m glad we’ll be able to make it available to other people,” said Martin Lawrence, a professor in Department of Chemistry and Biochemistry in MSU’s College of Letters and Science and the facility director of MSU’s Cryo-Electron Microscopy Laboratory, also called the Cryo-EM Lab.

Are you developing new software for an existing application? Did you know your development work could be eligible for the R&D Tax Credit and you can receive up to 14% back on your expenses? Even if your development isn’t successful your work may still qualify for R&D credits (i.e. you don’t need to have a patent to qualify). To find out more, please contact a Swanson Reed R&D Specialist today or check out our free online eligibility test.

Who We Are:

Swanson Reed is one of the U.S.’ largest Specialist R&D tax advisory firms. We manage all facets of the R&D tax credit program, from claim preparation and audit compliance to claim disputes.

Swanson Reed regularly hosts free webinars and provides free IRS CE and CPE credits for CPAs. For more information please visit us at www.swansonreed.com/webinars or contact your usual Swanson Reed representative.

BeyondSpring to Host R&D Day for Plinabulin

BeyondSpring Inc. is a global leader in biopharmaceuticals with focus on cancer therapies. They have recently announced their plans to host an R&D Day to discuss the development program for their novel immune agent – Plinabulin.

The R&D day will take place in late June with presentations from experts in the field who will highlight the unmet medical needs in treating patients with non-small cell lung cancer (NSCLC).

They will also discuss their pipeline as it applies to their lead asset plinabulin – a selective immunomodulating microtubule-binding agent (SIMBA). Their focus will specificall be on:

Plinabulin and G-CSF combination, which received priority review by the U.S. Food and Drug Administration (FDA) for its NDA for prevention of chemotherapy-induced neutropenia (CIN), which also received breakthrough designation. The Company has a PDUFA date of November 30, 2021.
Plinabulin and docetaxel combination, which is in a fully enrolled pivotal Phase 3 global study (DUBLIN-3) as a potential direct anticancer agent in patients with NSCLC. DUBLIN-3 is expected to report data in mid-2021.
Plinabulin in combination immune-oncology regimens, leveraging its MOA as a potent APC (antigen presenting cell) inducer. Plinabulin has demonstrated promising Phase 1 data in 2nd/3rd line SCLC (ASCO 2021); company has recently initiated a Phase 1 study in 7 cancers which failed checkpoint inhibitors to investigate plinabulin’s potential to reverse resistance to immunotherapy.

Are you developing new pharmaceuticals for an existing application? Did you know your development work could be eligible for the R&D Tax Credit and you can receive up to 14% back on your expenses? Even if your development isn’t successful your work may still qualify for R&D credits (i.e. you don’t need to have a patent to qualify). To find out more, please contact a Swanson Reed R&D Specialist today or check out our free online eligibility test.

Who We Are:

Swanson Reed is one of the U.S.’ largest Specialist R&D tax advisory firms. We manage all facets of the R&D tax credit program, from claim preparation and audit compliance to claim disputes.

Swanson Reed regularly hosts free webinars and provides free IRS CE and CPE credits for CPAs. For more information please visit us at www.swansonreed.com/webinars or contact your usual Swanson Reed representative.

MannKind and United Therapeutics Earn FDA Priority Review Status

New Jersey Patent of the Month - May 2021

The FDA has granted priority review status for Tyvaso DPI as it seeks approval. Tyvaso DPI is a dry powder inhaled formulation of treprostinil to treat pulmonary arterial hypertension (PAH) as well as pulmonary hypertension associated with the interstitial lung disease (PH-ILD).

This priority review process shortens the FDA review period to eight months rather than an entire year.

United Therapeutics developed Tyvaso DPI and submitted the new drug application and request for priority review in April. MannKind Corp. developed the handheld Dreamboat inhalation device used to deliver Tyvaso DPI.

This collaboration works to deliver Tyvaso DPI to patients so that the drug may lower blood pressure and improve patient health. Over the course of initial Phase 1 trials, patients showed improvement in their ability to perform exercise and reduced PAH symptoms overall.

In anticipation of transitioning from manufacturing Dreamboats for a small clinical supply to a larger prelaunch inventory, MannKind is scaling up its R&D facility in Danbury, Connecticut.

“It’s exciting to bring growth and expansion to Danbury and the surrounding communities as MannKind continues to build upon its Technosphere technology,” said Joe Kocinsky, MannKind’s chief technology officer. “Our site will practically double in size as we spend the next months preparing for Tyvaso DPI, pending FDA approval.”

Are you developing new technology for an existing application? Did you know your development work could be eligible for the R&D Tax Credit and you can receive up to 14% back on your expenses? Even if your development isn’t successful your work may still qualify for R&D credits (i.e. you don’t need to have a patent to qualify). To find out more, please contact a Swanson Reed R&D Specialist today or check out our free online eligibility test.

Who We Are:

Swanson Reed is one of the U.S.’ largest Specialist R&D tax advisory firms. We manage all facets of the R&D tax credit program, from claim preparation and audit compliance to claim disputes.

Swanson Reed regularly hosts free webinars and provides free IRS CE and CPE credits for CPAs. For more information please visit us at www.swansonreed.com/webinars or contact your usual Swanson Reed representative.

Amazon BMI Scanner Proves Accurate

North Carolina Patent of the Month - June 2021

Amazon has developed a body fat percentage scanner that works using your phone camera. Studies have recently come out showing that it is actually more accurate than the traditional measurement techniques.

This scan product is a part of Amazon’s Halo Body Feature, wherein the user takes four photos of their bodies. These are merged into a single 3D image and an algorithm uses this to calculate the user’s body fat percentage.

The study used data collected at two sites: Massachusetts General Hospital and Pennington Biomedical Research Center at Louisiana State University. It had 134 participants of varying body types and included 82 women and 52 men. Of the group, 81 were Caucasian, 32 were Black, nine were Asian, four were Hispanic, one was American Indian, and seven were multiracial. It’s a small number of people, but that’s typical with this type of research, which has to run people through expensive and unwieldy tests, Thomas says.

Each person in the study had their body fat percentage calculated through an X-ray technique that shows fat distribution through the body called dual-energy X-ray absorptiometry (DXA), which is the gold standard. The results from those scans were compared to the Amazon system, five scales that calculate body fat (two professional and three consumer), and something called air displacement plethysmography — which uses a pod-shaped device that measures how someone’s body displaces the air.

The study found that the body fat percentages calculated by Amazon Halo Body were closest to those calculated by DXA. It performed better than the air displacement plethysmography device, which is often used to calculate body fat by people studying weight and body composition, but is cumbersome and tricky to conduct correctly. The pods are expensive, have to be housed in a lab, and require people to wear swim caps and tight-fighting clothing.

While more validation studies are needed, developments like this can really restructure sectors of research. If accurate BMI is more readily available then body composition research faces one less limitation.

Are you developing new software for an existing application? Did you know your development work could be eligible for the R&D Tax Credit and you can receive up to 14% back on your expenses? Even if your development isn’t successful your work may still qualify for R&D credits (i.e. you don’t need to have a patent to qualify). To find out more, please contact a Swanson Reed R&D Specialist today or check out our free online eligibility test.

Who We Are:

Swanson Reed is one of the U.S.’ largest Specialist R&D tax advisory firms. We manage all facets of the R&D tax credit program, from claim preparation and audit compliance to claim disputes.

Swanson Reed regularly hosts free webinars and provides free IRS CE and CPE credits for CPAs. For more information please visit us at www.swansonreed.com/webinars or contact your usual Swanson Reed representative.